Insights into cellular factors that regulate HIV-1 replication in human cells
Identifieur interne : 000C43 ( Main/Exploration ); précédent : 000C42; suivant : 000C44Insights into cellular factors that regulate HIV-1 replication in human cells
Auteurs : Andrew Ml Lever ; Kuan-Teh JeangSource :
- Biochemistry [ 0006-2960 ] ; 2011.
Abstract
Retroviruses integrate into the host cell’s chromosome. Accordingly, many aspects of the life cycle of retroviruses like HIV-1 are intimately linked to the functions of cellular proteins and RNAs. In this review, we discuss in brief recent genome-wide screens for the identification of cellular proteins that assist HIV-1 replication in human cells. We also review findings on other cellular moieties that help or restrict the viral life cycle.
Url:
DOI: 10.1021/bi101805f
PubMed: 21218853
PubMed Central: 3035746
Affiliations:
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Le document en format XML
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